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The oxidative stress status of rats fed on oil bean seed meal

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Description

Abstract

This study was on oxidative stress status of rat fed with Pentraclethramacrophylla, otherwise known as African oil bean seed oil in English or Ugba in Igbo. Sixteen male rats were distributed into four groups. 1 (control), then group 2, 3, and 4 as test groups. They were fed with their formulated meal (5%, 10%, 20% inclusions)  for  28  days.  Group  1  was  the  control  and  were  fed  with  the  normal feed,  while  group  2,  3  and  4  which  were  the  test  groups  were  fed  with  test  feed formula.. The parameters determined were MDA concentrations and catalase activity.  Serum  MDA  significantly  increased  (p0.05)  while  the  catalase  activity significantly decreased (p0.05). This finding may be clinically significant to individuals with predisposition to increased generation of reactive oxygen species (ROS) and other degenerative diseases.

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